Do you think you're a good candidate for Citrulline supplementation? Now that you know more about who can benefit from Citrulline the most, as well as how you should take this amino acid to see the greatest results, are you ready to give it a try for yourself? Two ProSupps supplements combine Citrulline with other beneficial ingredients to help you get pumped and stay pumped after your workout is complete. Whichever pre-workout interests you, use our store locator today to find out where you can buy these great products online or in your area.
Posted in Perform. Allow Cookies. Train Gain Lean Perform. Advanced Search. Citrulline Malate vs. L-Citrulline When you're shopping for supplements that contain Citrulline, you'll likely notice that different supplements use different forms of this amino acid. Malic Acid is a natural supplement found in fruits like apples that helps to promote the creation of energy for your cells. L-Citrulline free form : L-Citrulline is an isolated form of Citrulline.
There is nothing else added to the amino acid when you take supplements that contain L-Citrulline. Who Should Take Citrulline? The following individuals will likely see the greatest benefits from adding it to their supplement regimen, though: Endurance athletes cyclists, runners, etc.
Strength athletes weightlifters, bodybuilders, etc. Those who enjoy the look of an enhanced post-workout pump Those who need help recovering faster from their workouts Those who want to feel focused and sharp, even without taking caffeine If any of those benefits appeal to you, chances are Citrulline will be a good addition to your supplement stack.
When Should You Take Citrulline? Citrulline is most commonly added to pre-workout supplements. Are There Any Side Effects? The following are some ingredients that often work with Citrulline to yield better results: Caffeine Caffeine is a stimulant that helps to increase energy levels and help you to feel more alert.
Combining caffeine with Citrulline may provide you with a better post-workout pump as well. Glycerol Glycerol is another common ingredient in pre-workout supplements. Taurine Taurine is an amino acid that also has antioxidant properties. Betaine Betaine is a plant compound found primarily in beets, but is also present in many other foods.
Theanine Theanine is an amino acid that's found mainly in tea especially green tea. Experience the Benefits of Citrulline Today Do you think you're a good candidate for Citrulline supplementation? Related Products. Recent posts. Sign In Create Account Sign in. If you have an account, sign in with your email address. Sign In. Forgot Your Password? Personal Information First Name. Last Name. Sign Up for Newsletter. If you are involved in strenuous physical activity on a daily basis or are concerned about your cardiovascular health, then look no further!
Citrulline is an amino acid that is considered nonessential because our bodies make a sufficient supply that dietary intake is not essential. L-citrulline malate is the chemical form of citrulline and can be used as a supplement. Citrulline can be obtained from food or our bodies can naturally produce it from ornithine, another amino acid obtained from food, through a biochemical process called the urea cycle.
Once your body metabolizes citrulline malate into citrulline, enzymes in the liver cell convert it into another amino acid called arginine, and then further enzymes convert arginine into nitric oxide in another process that also produces more citrulline molecules.
Nitric Oxide is a vasodilator that can help protect you from cardiovascular issues by helping to lower blood pressure and improve blood flow to your organs. Although our bodies produce citrulline, research shows that consuming citrulline as a supplement may have significant benefits. Research shows that using citrulline during exercise might enhance performance. There have been tests on animals that were fed citrulline: these animals were able to perform strenuous tasks for longer periods of time and had lower levels blood ammonia and lactate than the animals who were not given citrulline.
Several studies suggest that supplementation with citrulline malate may improve the health of your arteries and heart. Citrulline is synthesized made in the liver and intestine; its function is to detoxify ammonia and act as a vasodilator dilating the blood vessels.
Citrulline is also said to have an antioxidant effect. There are two forms of citrulline, available as a supplement; these include L-citrulline and citrulline malate. The primary difference between the two types of citrulline is that L-citrulline is simply citrulline without any other substance, and citrulline malate is comprised of L-citrulline, plus DL-malate a compound that may be instrumental in converting food to energy.
Although there is very little scientific research evidence to back many of the claims of L-citrulline health benefits, the natural supplement is said to have several health promoting properties, and is used for health conditions, including:. Athletic Performance. A randomized double-blind study the gold standard of research studies involving 41 men, discovered that a single dose of citrulline malate CM resulted in a significant increase in the number of barbell bench presses accounting for Another study, published in , looking at older individuals found citrulline modestly increased muscle blood flow during submaximal exercise in men but not women.
The same study found that the diastolic blood pressure of the treated group was lowered in men but not women. Cardiovascular Heart and Blood Vessel Health Studies have shown that short-term L-citrullline supplementation can lower blood pressure in adults with hypertension high blood pressure and those with pre-hypertension. A paper published in reviewed 8 trials looking at adults. Their analysis of the data suggested citrulline can lower systolic blood pressure by 4 mmHg.
A significant decrease in diastolic blood pressure was seen only at higher doses. The authors felt it was too soon to recommend citulline supplements but that a diet rich in citrulline containing foods might contribute to the prevention of hypertension.
Erectile Dysfunction. L-citrulline is said to boost L-arginine, which in turn helps to elevate nitrogen oxide NO synthesis. NO promotes the relaxation of blood vessels, resulting in oxygen-rich blood circulating through the arteries. Therefore, L-arginine is said to promote heart health, but it is also important in erectile function because of its blood flow promotion properties.
Its role as an alternative treatment for mild to moderate ED, particularly in patients with a psychological fear of phosphodiesterase type-5 enzyme inhibitors, deserves further research. Sickle Cell Disease. Studies have shown that some symptoms of sickle cell disease may be alleviated by taking a twice daily dose of L-citrulline by mouth. Not only was blood health improved with the administration of citrulline, study subjects also realized an improvement in overall well-being.
A double-blind clinical research study involving study participants with sickle cell anemia SCA discovered a link between an increased level of NO and a decrease in the frequency that the study subjects experienced pain. L-citrulline is thought to promote an increase in the level of NO in the body, as well as promoting L-arginine levels.
This study found that L-arginine supplementation may serve to potentiate the treatment of sickle cell anemia, but the study authors explained that more research is needed to evaluate the long-term safety and efficacy of these natural supplements. In the body, L-citrulline is transformed into a different amino acid, called L-arginine, which is converted into a chemical called nitric oxide. It is thought that L-citrulline may help to supply the body with the raw material it requires to make specific proteins.
L-citrulline may also act as a vasodilator a substance that widens the veins and arteries to help improve blood flow while lowering blood pressure. Citrulline has been used as an oral by mouth supplement for many years, without reports of serious safety concerns.
A contraindication is a treatment, medication, or procedure such as surgery that is not recommended because of a high potential of causing harm to the patient. It may also indicate that two specific medications including prescription drugs, over the counter medications and natural supplements should not be given together. Contraindications for L-citrulline include:. Those who are taking certain prescription drugs should not take citrulline, these include:.
Other prescription medications could interact with citrulline and it could have a negative impact on certain clinical states such as those with associated hypotension , hence its possible use should be discussed with a physician. The FDA notes that limited safety data is available so safety issues cannot be ruled out. L-citrulline is commonly available in a powder form that can be mixed with liquid or added to nutritional shakes.
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